BUFFER ADDITIVES OTHER THAN THE SURFACTANT SODIUM DODECYL-SULFATE FORPROTEIN SEPARATIONS BY CAPILLARY ELECTROPHORESIS

The different compounds utilized as additives to the electrolyte solut ions employed in protein capillary zone electrophoresis (CZE) for mini mizing protein-capillary wall interactions, for improving selectivity and resolution and for controlling the electroosmotic flow are reviewe d. The dependence of the electroosmotic flow on the different variable s that can be affected by the incorporation of an additive into the el ectrolytic solution is discussed. A list of the most effective additiv es employed for protein separations by CZE is reported in Appendix A. (C) 1997 Elsevier Science B.V.