THE INTENSITY OF TUMOR INFILTRATION WITH GRANULAR LEUKOCYTES AT DIFFERENT STAGES OF THE LEWIS LUNG-CARCINOMA PROGRESSION - THE INFLUENCE OFTHE PRIMARY TUMOR SURGERY

The intensity of infiltration of the primary tumour and its lung metas tases with granular leucocytes and lymphmocytes was studied in mice wi th Lewis lung carcinoma. The content of lymphocytes decreases, while t hat of granular leucocytes increases with the growth of the primary tu mour. The relative content of lymphocytes in metastasis tumours is hig her than that of granular leucocytes. The primary tumour surgery cause s reliable changes in the intensity of tumour infiltration with these cells, as compared with non-operated animals.