POLANDS-SYNDROME AND WILMS-TUMOR - AN UNUSUAL ASSOCIATION

Poland's syndrome, a rare congenital disorder with pectoralis muscular girdle defect, have been reported in association with lymphoreticular malignancies in the past. Childhood solid tumors in association with this congenital anomaly have not been reported so far. We describe thi s rare association of Poland's syndrome and Wilms tumor. Due to the po ssibility of increased risk of leukemogenesis in patients with Poland' s syndrome, chemo-radiation therapy of Wilms tumor in our patient may increase the risk of secondary leukemia. Therapeutic modification of p rimary cancer in these patients may be necessary with careful long-ter m follow-up for early detection and treatment of secondary cancer. (C) 1998 Wiley-Liss, Inc.