BACKGROUND. Recent studies have shown that char-free pulsed carbon dio
xide lasers are useful in the treatment of rhytids. Other infrared las
ers have also been observed to induce changes in the skin. OBJECTIVE.
In this pilot study, we evaluated the rhytid resurfacing capability of
the Q-switched neodymium:yttrium-aluminum-garden (QS Nd:YAG) laser at
1064 nm as compared with char-free carbon dioxide lasers at 10,600 nm
. METHODS. Three lasers were used in the study: The QS Nd:YAG laser, t
he SilkTouch carbon dioxide laser, and the UltraPulse carbon dioxide l
aser. Eleven subjects were treated in either the periorbital or perior
al region with the QS Nd:YAG laser on one side of the face, and both o
f the char-free pulsed carbon dioxide lasers on the other side. The su
bjects were evaluated at posttreatment days 7, 30, 60, and 90 for impr
ovement of rhytids, healing, pigmentary changes, and erythema. RESULTS
. All II patients treated with the char-free carbon dioxide lasers imp
roved. Nine of 11 patients treated with the QS Nd:YAG laser were impro
ved. Healing (complete reepithelialization) was noted to occur 3-6 day
s earlier in sites treated with the RS Nd:YAG than in sites treated wi
th char-free carbon dioxide lasers. Pigmentary changes were not observ
ed in any treatment site. Erythema was observed at 1 month after treat
ment in all areas treated with the char-free carbon dioxide lasers, bu
t only three patients treated with the QS Nd:YAG exhibited erythema. T
hese were the same three QS Nd:YAG-treated patients whose clinical imp
rovement was comparable with that of the char-free carbon dioxide lase
rs. CONCLUSION. The Q-switched Nn:YAG laser may play a role in the tre
atment of rhytids. (C) 1997 by the American Society for Dermatologic S
urgery, Inc.