PREPARATION, ANTIMICROBIAL EVALUATION, AND MUTAGENICITY OF ARYL]-[1-METHYL-5-NITRO-1H-2-IMIDAZOLYL]METHANOLS, HENYL]-[1-METHYL-5-NITRO-1H-2-IMIDAZOLYL]METHANOL, AND [2-HYDROXYARYL]-[1-METHYL-5-NITRO-1H-2-IMIDAZOLYL] KETONES

Authors
ARREDONDO Y MORENOMANAS M PLEIXATS R PALACIN C RAGA MM CASTELLO JM ORTIZ JA
Citation
Y. Arredondo et al., PREPARATION, ANTIMICROBIAL EVALUATION, AND MUTAGENICITY OF ARYL]-[1-METHYL-5-NITRO-1H-2-IMIDAZOLYL]METHANOLS, HENYL]-[1-METHYL-5-NITRO-1H-2-IMIDAZOLYL]METHANOL, AND [2-HYDROXYARYL]-[1-METHYL-5-NITRO-1H-2-IMIDAZOLYL] KETONES, Bioorganic & medicinal chemistry, 5(10), 1997, pp. 1959-1968
Citations number
34
Categorie Soggetti
Biology,"Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry → ACNP
ISSN journal
09680896
Volume
5
Issue
10
Year of publication
1997
Pages
1959 - 1968
Database
ISI
SICI code
0968-0896(1997)5:10<1959:PAEAMO>2.0.ZU;2-V
Abstract
Efficient preparations of the titled compounds are described, their an timicrobial activity and mutagenic properties being evaluated. Some of the studied compounds are nonmutagenic and present a MIC as low as so me of the usual standards in the field. (C) 1997 Elsevier Science Ltd.