GLUCOSE-TRANSPORTER GLUT-5 EXPRESSION IN MICROGLIAL CELLS

Glut 5 is a member of a family of facilitative glucose transporter pro teins that are involved in the transportation of glucose and/or fructo se across plasma membranes. Glut 5 is one of three isoforms expressed in brain. Using immunocytochemical and immunoblotting techniques in fo rmalin fixed tissue, we have shown that Glut 5 is exclusively expresse d in microglial cells of the human and rat brain. Our data demonstrate that unlike other microglial markers, Glut 5 can be used as a microgl ial marker in formalin fixed tissue. (C) 1997 Wiley-Liss, Inc.