CERVICAL SARCOMA BOTRYOIDES AND OVARIAN SERTOLI-LEYDIG CELL TUMOR

The case of a woman who developed a cervical sarcoma botryoides tumor at age 14 years and a right ovarian Sertoli-Leydig cell tumor with alp ha-fetoprotein production at 27 years is presented. The sarcoma botryo ides was a stage Ib, 4-cm, polypoid ectocervical tumor treated by radi cal hysterectomy and bilateral pelvic lymphadenectomy, The Sertoli-Ley dig cell tumor was a stage la, 145-g mass removed piecemeal by right o ophorectomy. Histologically, it was an intermediate Sertoli-Leydig cel l tumor with a heterologous element composed of an endometrioid-like y olk sac tumor which was producing alpha-fetoprotein. There was no hist ological similarity between the two tumors, The patient is alive witho ut evidence of disease, 16 years after diagnosis of her sarcoma botryo ides and 3 years after her Sertoli-Leydig cell tumor, This is, to our knowledge, the third known association between these two rare gynecolo gical tumors. The basis of the association remains unknown. (C) 1997 A cademic Press.