The recognition of onchocerciasis as a major public health problem in
the savanna belts of West Africa resulted in the establishment of the
Onchocerciasis Control Programme (OCP) in 1974. Control was initially
based on vector control by weekly larviciding. The OCP is now in trans
ition towards its Fnal phase in which repented treatment with ivermect
in, a safe and effective microfilaricide, is incorporated with vector
control, or in certain circumstances is used alone. Ivermectin distrib
ution hingeing on sustainable community systems is the basis of a new
programme in endemic African countries outside the OCP and in the Amer
icas. David Molyneux and John Davies describe the latest trends and de
velopments related to onchocerciasis control.