PREPARATION OF POLYSTYRENE RESINS CONTAINING CHIRAL GROUPS DERIVED FROM AMINO-ACIDS

A general methodology has been evaluated for the preparation of polyst yrene-divinylbenzene resins which contain chiral groups derived from s imple aminoacids. This approach requires the initial anchoring of an a minoacid methyl ester followed by the modification of the resulting po lymers using solid-phase techniques. The appropriate transformations o f the supported chiral groups can be accomplished very efficiently. Re sults obtained are much better than those described for similar reacti ons carried out in solution.