Serotonin is an important brain chemical that acts as a neurotransmitt
er to communicate information among nerve cells. Serotonin's actions h
ave been linked to alcohol's effects on the brain and to alcohol abuse
, Alcoholics and experimental animals that consume large quantities of
alcohol show evidence of differences in brain serotonin levels compar
ed with nonalcoholics, Both short-and long-ft rm alcohol exposure also
affect the serotonin receptors that convert the chemical signal produ
ced by serotonin into functional changes in the signal-receiving cell.
Drugs that act on these receptors alter alcohol consumption in both h
umans and animals. Serotonin, along with other neurotransmitters, also
may contribute to alcohol's intoxicating and rewarding effects, and a
bnormalities in the brain's serotonin system appear to play an importa
nt role in the brain processes underlying alcohol abuse.