SEROTONINS ROLE IN ALCOHOLS EFFECTS ON THE BRAIN

Authors
Citation
Dm. Lovinger, SEROTONINS ROLE IN ALCOHOLS EFFECTS ON THE BRAIN, Alcohol health and research world, 21(2), 1997, pp. 114-120
Citations number
28
Categorie Soggetti
Substance Abuse
ISSN journal
0090838X
Volume
21
Issue
2
Year of publication
1997
Pages
114 - 120
Database
ISI
SICI code
0090-838X(1997)21:2<114:SRIAEO>2.0.ZU;2-O
Abstract
Serotonin is an important brain chemical that acts as a neurotransmitt er to communicate information among nerve cells. Serotonin's actions h ave been linked to alcohol's effects on the brain and to alcohol abuse , Alcoholics and experimental animals that consume large quantities of alcohol show evidence of differences in brain serotonin levels compar ed with nonalcoholics, Both short-and long-ft rm alcohol exposure also affect the serotonin receptors that convert the chemical signal produ ced by serotonin into functional changes in the signal-receiving cell. Drugs that act on these receptors alter alcohol consumption in both h umans and animals. Serotonin, along with other neurotransmitters, also may contribute to alcohol's intoxicating and rewarding effects, and a bnormalities in the brain's serotonin system appear to play an importa nt role in the brain processes underlying alcohol abuse.