O. Shinohara et al., SPONTANEOUS REDUCTION OF A RECURRENT CRANIOPHARYNGIOMA IN AN 8-YEAR-OLD FEMALE-PATIENT - CASE-REPORT, Neurosurgery, 41(5), 1997, pp. 1188-1190
OBJECTIVE AND IMPORTANCE: The spontaneous rupture of a craniopharyngio
ma is an extremely rare condition confined to adults. This is the firs
t report of a patient younger than 10 years who experienced spontaneou
s reduction (possibly rupture) of a craniopharyngioma. CLINICAL PRESEN
TATION: An 8-year-old female patient with a recurrence of a craniophar
yngioma experienced fever, headache, and visual disturbance that laste
d a few days. Concurrent with the improvement of these symptoms, marke
d reduction in the size of the tumor was revealed using magnetic reson
ance imaging, suggesting the occurrence of a rupture. INTERVENTION: Su
bsequent magnetic resonance imaging of the hypothalamic-pituitary regi
on was performed while the patient received growth hormone therapy. CO
NCLUSION: There was no increase in the size of the tumor 1 year after
the reduction occurred. Prompt evaluation of the hypothalamic-pituitar
y region using magnetic resonance imaging is warranted to rule out the
possibility of spontaneous reduction (including rupture) of the tumor
in a ii situation in which the patient with a craniopharyngioma shows
meningeal signs or a rapid change of neurological symptoms (such as h
eadache, fever, or visual disturbance).