INFLUENCE OF DISSOLVED O-2 ON THE FERMENTATIVE PRODUCTION OF GALLIDERMIN BY STAPHYLOCOCCUS-GALLINARUM

Authors
KEMPF M THEOBALD U FIEDLER HP
Citation
M. Kempf et al., INFLUENCE OF DISSOLVED O-2 ON THE FERMENTATIVE PRODUCTION OF GALLIDERMIN BY STAPHYLOCOCCUS-GALLINARUM, Biotechnology letters, 19(11), 1997, pp. 1063-1065
Citations number
9
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
19
Issue
11
Year of publication
1997
Pages
1063 - 1065
Database
ISI
SICI code
0141-5492(1997)19:11<1063:IODOOT>2.0.ZU;2-S
Abstract
Decreased O-2 supply during the fermentative production of gallidermin by Staphylococcus gallinarum decreased biomass formation by 65% compa red to that obtained with optimal oxygen supply. However the antibioti c, gallidemin, increased by more than 50% at the same time. This effec t was used in a process strategy, that allows biomass formation under oxygen saturation first and then switches to a prolonged production ph ase after a carefully directed shift to oxygen limitation.