ASTAXANTHIN PRODUCTION BY PHAFFIA-RHODOZYMA ENHANCED IN FED-BATCH CULTURE WITH GLUCOSE AND ETHANOL FEEDING

Authors
YAMANE Y HIGASHIDA K NAKASHIMADA Y KAKIZONO T NISHIO N
Citation
Y. Yamane et al., ASTAXANTHIN PRODUCTION BY PHAFFIA-RHODOZYMA ENHANCED IN FED-BATCH CULTURE WITH GLUCOSE AND ETHANOL FEEDING, Biotechnology letters, 19(11), 1997, pp. 1109-1111
Citations number
10
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
19
Issue
11
Year of publication
1997
Pages
1109 - 1111
Database
ISI
SICI code
0141-5492(1997)19:11<1109:APBPEI>2.0.ZU;2-C
Abstract
Of various carbon sources, examined for the cultivation of Phaffia rho dozyma, ethanol enhanced the astaxanthin content but severely decrease d growth. Therefore, high cell mass was obtained by glucose fed-batch culture with pH-stat, and the ethanol feeding was performed based on D O-stat. As a result of this two-stage fed-batch cultivation, 30 g dry cells per liter were obtained, and the astaxanthin content reached 0.7 2 mg/g, which was 2.2-fold higher than that without ethanol feeding.