D. Fasquelle et al., SINUSITIS EPIDEMIOLOGY - A STUDY OF 326 S INUS ASPIRATES SAMPLED BETWEEN 1993 AND 1996, Medecine et maladies infectieuses, 27(8-9), 1997, pp. 792-799
326 sinus aspirates were sampled in an ENT Unit from 270 patients betw
een January 1993 and June 1996. All the samples were analyzed in the M
icrobiology Laboratory. Sinusitis was maxillary in 93.9 % of the cases
. Sinus aspirates were sampled in 85 acute sinusitis, 93 sub-acute sin
usitis, and 148 chronic sinusitis cases. Cultures were positive in 166
cases (50.9 %) but pathogen bacteria were found only in 143 cases: on
e microorganism was isolated 123 times and associated bacteria 20 time
s. The most frequent strains were: Hemophilus influenzae (30), Strepto
coccus pneumoniae (23), Staphylococcus aureus (21), and Pseudomonas ae
ruginosa (19). Isolated bacteria were different according to the type
of sinusitis: S. pneumoniae and H. influenzae were the most frequent b
acteria in acute or subacute sinusitis. S. aureus, H. influenzae and P
. aeruginosa were the most frequent bacteria in chronic sinusitis. Sus
ceptibility to antibiotics was studied through the disk method. The re
sults for 142 aerobic strains were: 81 % of bacteria susceptible to am
oxicillin associated with clavulanic acid; 75.3 % to pristinamycin; 73
.2 % to cefuroxime; 64.1 % to cefpodoxime; 53.5 % to ofloxecin, and on
ly 43 % io cefixime. For the last 66 strains: 78.8 % susceptible to sp
arfloxacin, and 69.7 % to cefotiam. We have found 9/23 S. pneumoniae w
ith decreased susceptibility to penicillin and 9/29 H. influenzae prod
ucing beta-lactamase.