Db. Roth et al., VISUAL RESULTS AFTER SUBMACULAR SURGERY FOR NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION, Ophthalmic surgery, 28(11), 1997, pp. 920-925
BACKGROUND AND OBJECTIVE: Submacular membranectomy has been proposed a
s a treatment option for subfoveal choroidal neovascular membranes (CN
VMs). The authors reviewed the visual outcomes of patients who underwe
nt surgical removal of subfoveal CNVMs caused by age-related macular d
egeneration (ARMD). PATIENTS AND METHODS: Thirty-eight patients (38 ey
es) were retrospectively reviewed. Selection criteria included: (I) th
e presence of a well-demarcated subfoveal CNVM on fluorescein angiogra
phy; (2) best-corrected Snellen visual acuity reduced to the level of
20/200 or worse; and (3) no other eye disease that could compromise vi
sual acuity. Pars plana vitrectomy, retinotomy, and membrane removal w
ere performed to remove the subfoveal choroidal neovascular complex wi
th minimal disruption of the surrounding tissues. A significant change
was defined as a two-line difference from best-corrected preoperative
visual acuity on the Snellen chart. RESULTS: At 3 months postoperativ
ely, 7 (18.4%) of the 38 eyes had improved, 8 (21.1%) of the eyes had
worsened, and 23 (60.5%) of the eyes had remained unchanged. The final
visual acuity improved in 8 (21.1%) of the eyes, worsened in 11 (28.9
%) of the eyes, and remained unchanged in 19 (50%) of the eyes. The av
erage follow-up time was 632 days. CONCLUSIONS: The authors employed a
minimally invasive approach to the removal of CNVMs in ARMD. Neverthe
less, the resultant visual acuity was often unsatisfactory. Therefore,
the authors recommend not operating on ARMD-associated subfoveal CNVM
s with the current technology.