DIFFERENT MORPHOMETRIC AND DENSITOMETRIC PARAMETERS PREDICT CERVICAL AND TROCHANTERIC HIP FRACTURE - THE EPIDOS STUDY

Citation
F. Duboeuf et al., DIFFERENT MORPHOMETRIC AND DENSITOMETRIC PARAMETERS PREDICT CERVICAL AND TROCHANTERIC HIP FRACTURE - THE EPIDOS STUDY, Journal of bone and mineral research, 12(11), 1997, pp. 1895-1902
Citations number
20
Categorie Soggetti
Endocrynology & Metabolism
ISSN journal
08840431
Volume
12
Issue
11
Year of publication
1997
Pages
1895 - 1902
Database
ISI
SICI code
0884-0431(1997)12:11<1895:DMADPP>2.0.ZU;2-0
Abstract
We used an experimental software measuring the hip axis length (HAL) a nd bone mineral density (BMD) in specific regions of the lower and upp er part of the femoral neck on dual-energy X-ray absorptiometry scans, To determine whether these parameters were significant predictors of the type of hip fracture, we measured 167 healthy women (controls), 24 women with trochanteric, and 42 women with cervical hip fractures wit hin the EPIDOS prospective cohort, EPIDOS is a multicenter prospective study on risk factors for hip fracture performed in 7575 elderly wome n living at home, aged 75-95 and conducted in five French centers (Ami ens, I;yon, Montpellier, Paris, Toulouse), Measurements were performed on data acquired at baseline before the occurrence of fracture, In th e cervical fracture group, HAL was significantly longer than in contro ls (94.2 vs, 92.3, p = 0.03), and the associated odds ratio (OR) adjus ted for age, weight, and total femoral neck BMD was significant (OR = 1.64, 95% confidence interval [CI] 1.06-2.55), In contrast, HAL was no t significantly different from controls in the trochanteric fracture g roup, Femoral neck diameter,vas not a predictor of fracture, The upper and lo,ver femoral neck BMD was lower in the trochanteric fracture gr oup than in controls, and both measurements predicted trochanteric fem oral neck fracture, In contrast, the prediction of cervical femoral ne ck fracture was enhanced by measuring only the upper part of the femor al neck (OR = 2.79 vs, 1.97 for the total femoral neck) while BMD of t he lower part was not different from controls, Hip axis length is a pr edictor of femoral neck fracture, Femoral neck BMD distribution is dif ferent between cervical and trochanteric fractures, These results supp ort the hypothesis of a different pathophysiological mechanism between the two types of hip fractures.