In-line blood warmers increase the extracorporeal volume of apheresis
procedures. A saline rinse of the blood warmer may be employed to mini
mize the loss of red blood cells (RBCs) from this extra volume. We mea
sured the amount of RBCs remaining in three different brands of blood
warmers at the end of a COBE Spectra rinsebock to determine the clinic
al significance of blood warmer saline rinses. The volume of RBCs remo
ved by a warmer rinse ranged from 15 to 24 ml per procedure and was st
atistically different among the three brands of warmers. The COBE warm
er contained significantly less RBCs than either the Fenwal or Pharmas
eal warmers. Patient hematocrit was not highly correlated with the res
idual RBC volume (r = 0.30). We estimate that 15-20 procedures are req
uired before the equivalent of one unit of packed RBCs is lost to bloo
d warmers. We conclude that the blood warmer saline rinse may be safel
y omitted for most patients. (C) 1997 Wiley-Liss, Inc.