Measurement of Endexpiratory CO2 Pressure for Detecting Ovulation: The
time course of the endexpiratory pressure of CO2 was determined daily
during the menstrual cycle of 15 volunteers and related to the change
s in LH, E2 and P-4 serum concentrations and the basal body temperatur
e. PCO2 Values were significantly higher during the follicular phase o
f the cycle than during the luteal phase. In contrast to the basal bod
y temperature shift that occurs after the LH-surge, the changes of pCO
(2) became significant already preovulatorily, 1 - 2 days befor the LH
-peak. The pCO(2) level did not exhibit any diurnal or circadian rhyth
m and did not seem to be influenced by physical activity. Determinatio
n of pCO(2) appears to be a simple method for detecting ovulation. it
may be clinically useful for contraception as well as for planned conc
eption.