SEVERE POSTPARTUM BLEEDING AND APC RESIST ANCE - CASE-REPORT

Severe Postpartum Bleeding and APC Resistance - Case Report: We report on a spontaneous vaginal delivery of a 35-year old woman (Grav VI/Par III) the 38th gestational week. The postpartal period was complicated by severe postpartum bleeding. The patient was diagnosed to suffer fr om APC resistance. APC resistance is the most common cause of heredita ry thromobembolic complications. There is a resulting hypercoagulabili ty of blood because of the resistance against activated protein C. We therefore conclude that APC resistance could lead to hypercoagulation and may by the means of coagulopathy aggravate uterine postpartum blee ding complications. In case of pregnancy and delivery not only thrombo embolic complications but also the development of severe bleeding comp lications should be kept in mind prospectively.