Background: Increasing migration of sex workers across East European b
orders into Turkey has resulted in increased arrests of unregistered s
ex workers. There is concern regarding the prevalence of sexually tran
smitted diseases (STD) such as C. trachomatis in this unregulated grou
p. Objective: To measure the prevalence of C. trachomatis infection an
d selected related demographic and behavioral factors among registered
and unregistered sex workers in Istanbul, Turkey. Methods: In a cross
-sectional study, the prevalence of C. trachomatis infection was studi
ed by direct fluorescent antibody testing in 248 sex workers: 158 pres
ented for routine medical screening and 90 who were arrested for lack
of registration. All subjects were interviewed regarding demographic f
actors, sexual activity, and antibiotic and drug use. Results: The ove
rall C. trachomatis prevalence was 12.9% (12.0% registered and 14.4% u
nregistered). There was a strong association between never using condo
ms and chlamydia positivity (odds ratio 8.9 [95% confidence interval 3
.7 to 21.6]). Conclusions: The high rate of C trachomatis among all te
sted sex workers and the lack of regular condom use, particularly amon
g unregistered sex workers, indicate that there is an urgent need for
safe sex education and continued STD screening of unregistered sex wor
kers.