OXYGEN RADICALS AND RENAL DISEASES

Authors
KLAHR S
Citation
S. Klahr, OXYGEN RADICALS AND RENAL DISEASES, Mineral and electrolyte metabolism, 23(3-6), 1997, pp. 140-143
Citations number
32
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Mineral and electrolyte metabolism → ACNP
ISSN journal
03780392
Volume
23
Issue
3-6
Year of publication
1997
Pages
140 - 143
Database
ISI
SICI code
0378-0392(1997)23:3-6<140:ORARD>2.0.ZU;2-G
Abstract
Reactive oxygen metabolites (superoxide, hydrogen peroxide, hydroxyl r adical, and hypochlorous acid) are important mediators of renal damage in acute renal failure and glomerular and tubulointerstitial diseases . The role of these oxygen metabolites in the above entities is discus sed, and the effects of antioxidants and scavengers of O-2, radicals a re considered. The role of oxygen radicals in the regulation of gene t ranscription is also considered.