STUDIES ON FUSED PYRIMIDINE-DERIVATIVES .13. THERMAL ENE REACTION OF 6-(ALK-2-ENYLAMINO)-5-[(SUBSTITUTED O)METHYL]-1,3-DIMETHYLPYRIMIDINE-2,4(1H,3H)-DIONES LEADING TO PYRIMIDO[4,5-B]AZEPINES
T. Inazumi et al., STUDIES ON FUSED PYRIMIDINE-DERIVATIVES .13. THERMAL ENE REACTION OF 6-(ALK-2-ENYLAMINO)-5-[(SUBSTITUTED O)METHYL]-1,3-DIMETHYLPYRIMIDINE-2,4(1H,3H)-DIONES LEADING TO PYRIMIDO[4,5-B]AZEPINES, Journal of the Chemical Society. Perkin transactions. I, (5), 1994, pp. 565-570
6-(Alk-2-enylamino)-1,3-dimethyl-5-[(substituted imino)methyl] pyrimid
ine-2,4(1 H,3H)-diones, obtained from -5-formyl-1,3-dimethylpyrimidine
-2,4(1H,3H)-diones 1 and primary amines, participate in the intramolec
ular ene reaction (Type III) leading to pyrimido[4.5-b]azepine derivat
ives.