O. Toledano et S. Magdassi, FORMATION OF SURFACE-ACTIVE GELATIN BY COVALENT ATTACHMENT OF HYDROPHOBIC CHAINS, Journal of colloid and interface science, 193(2), 1997, pp. 172-177
Surface active gelatin was formed by covalent attachment of hydrophobi
c groups to gelatin molecules, The modification was carried out at var
ious degrees of attachment and with various chain lengths. These modif
ied gelatins (MGs) were synthesized in dry DMSO by a simple and rapid
method. The new method leads to high yields and allows high degrees of
modification. The MGs, which have various hydrophobicities, have bett
er surface activity than the native gelatin, as determined by surface
tension reduction. The surface tension reduction is correlated to the
hydrophobicity of the modified molecule, which was determined by a flu
orescent probe. It appears that both the increase in the number of the
hydrophobic groups and the increase in the chain lengths lead to decr
eased surface tension. (C) 1997 Academic Press.