OCHRATOXIN-A IN THE SERA OF BLOOD-DONORS AND ILL PERSONS

Ochratoxin A has been determined in the sera of healthy volunteer bloo d donors and ill persons. The polyclonal antibody-based ELISA techniqu e was used for screening. Ochratoxin-A could be detected in the sera o f many healthy volunteer blood donors. The rate of the ochratoxin-posi tive sera was high (73.74 %) with about 20 % difference between blood donors and ill persons. No correlation could be detected between the s erum-level of Ochratoxin A and the different types of diseases. The te sting of the monoclonal antibody-based ELISA technique (Toxiklon OA en zyme immunoassay kit Agricultural Biotechnology Center, Godollo, Hunga ry) and confirmation of the positive samples with HPLC are in progress .