REEXAMINATION OF RESPIRATION-IMPAIRING EFFECT OF BIKAVERIN ON ISOLATED-MITOCHONDRIA

Authors
KITAGAWA A SUGIHARA Y OKUMURA M KAWAI K HAMASAKI T
Citation
A. Kitagawa et al., REEXAMINATION OF RESPIRATION-IMPAIRING EFFECT OF BIKAVERIN ON ISOLATED-MITOCHONDRIA, Cereal Research Communications, 25(3), 1997, pp. 451-452
Citations number
4
Categorie Soggetti
Agriculture
Journal title
Cereal Research Communications → ACNP
ISSN journal
01333720
Volume
25
Issue
3
Year of publication
1997
Part
1
Pages
451 - 452
Database
ISI
SICI code
0133-3720(1997)25:3<451:ROREOB>2.0.ZU;2-7
Abstract
Bikaverin was examined for the respiration-impairing effect, using iso lated rat liver mitochondria and submitochondrial particles (SMP). It was concluded that bikaverin repressed both NAD- and succinate-linked respirations at low concentrations, and uncoupled oxidative phosphoryl ation in consequence of the lysis (swelling) of inner mitochondrial me mbranes at high concentrations.