TOTAL SYNTHESIS OF CARBOCYCLIC NIKKOMYCIN-C

Authors
WARD SE HOLMES AB MCCAGUE R
Citation
Se. Ward et al., TOTAL SYNTHESIS OF CARBOCYCLIC NIKKOMYCIN-C, Chemical communications, (21), 1997, pp. 2085-2086
Citations number
26
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
21
Year of publication
1997
Pages
2085 - 2086
Database
ISI
SICI code
1359-7345(1997):21<2085:TSOCN>2.0.ZU;2-M
Abstract
The carbocyclic analogue 11 of nikkomycin C 1 is prepared by a sequenc e involving allylic rearrangement of the imino ester adduct 3, palladi um-mediated substitution of the allylic lactone 4c with uracil bis(tri methylsilyl)ether 6, and osmylation of the double bond.