THE ISOMERIZATION CHLORINATION OF O,O-DIALKYL-PHENYLTHIOPHOSPHONATES WITH PHOSPHORUS OXYCHLORIDE - A NEW CONVENIENT SYNTHESIS OF S-ALKYL-PHENYLTHIOPHOSPHONIC ACID-DERIVATIVES
Cc. Tang et al., THE ISOMERIZATION CHLORINATION OF O,O-DIALKYL-PHENYLTHIOPHOSPHONATES WITH PHOSPHORUS OXYCHLORIDE - A NEW CONVENIENT SYNTHESIS OF S-ALKYL-PHENYLTHIOPHOSPHONIC ACID-DERIVATIVES, Phosphorus, sulfur and silicon and the related elements, 84(1-4), 1993, pp. 159-164
A new method for the synthesis of S-alkyl phenylthiophosphonic acid de
rivatives is reported. The chlorination of O,O-dialkyl phenylthiophosp
honates with phosphorus oxychloride proceeds with isomerization to giv
e S-alkyl phenylthiophosphonochloridates, which react further with var
ious nucleophiles in the presence of triethylamine to give the title c
ompounds.