MELANOMA ARISING IN A CERVICAL SPINAL NERVE ROOT - REPORT OF A CASE WITH A BENIGN COURSE AND MALIGNANT FEATURES

Citation
So. Skarli et al., MELANOMA ARISING IN A CERVICAL SPINAL NERVE ROOT - REPORT OF A CASE WITH A BENIGN COURSE AND MALIGNANT FEATURES, Neurosurgery, 34(3), 1994, pp. 533-537
Citations number
24
Categorie Soggetti
Surgery,Neurosciences
Journal title
ISSN journal
0148396X
Volume
34
Issue
3
Year of publication
1994
Pages
533 - 537
Database
ISI
SICI code
0148-396X(1994)34:3<533:MAIACS>2.0.ZU;2-K
Abstract
A 20-YEAR-OLD CAUCASIAN woman with a 5-year history of right arm, neck , and back pain sought treatment when an automobile accident (4 months before admission) exacerbated her pain. Magnetic resonance imaging re vealed an intra- and extradural mass compressing the spinal cord at th e C5-C6 level. It also extended into and widened the neural foramen, m imicking a neurofibroma. A single cafe-au-lait spot was discovered in the inguinal region. A two-staged surgical resection was performed on an apparent hemorrhagic C6 nerve root mass. The mass exhibited diagnos tic features of a malignant melanoma histologically, immunocytochemica lly, and ultrastructurally. A search for a primary lesion outside the nervous system or other metastases during an 8-year period from the on set of symptoms has been negative. The patient's chronic history, evid ence of neural foraminal enlargement, and the absence of other maligna nt melanoma lesions or subsequent metastases indicates that this lesio n may be a primary melanoma of the nerve root with a benign course.