El. Gollub et al., COOCCURRENCE OF AIDS AND TUBERCULOSIS - RESULTS OF A DATABASE MATCH AND INVESTIGATION, Journal of acquired immune deficiency syndromes and human retrovirology, 16(1), 1997, pp. 44-49
Purpose: To conduct a match between the AIDS and Tuberculosis (TB) Reg
istries in Philadelphia. Methods: Database extracts for the year 1993
were prepared manually and matched by name, birth date, and social sec
urity number. Reported cases not matching with those on the primary re
gistry were investigated. Proportion levels of comorbidity were calcul
ated. Predictors of comorbidity were evaluated separately for the TB s
ample and for the AIDS sample. Results: The proportion of comorbid pat
ients with AIDS alive at midyear was 4.7%; 17.1% of TB cases were also
HN-positive. Twenty-three percent of AIDS cases were falsely reported
as having active TB; the false-positive rate in TB Control for HIV se
ropositivity was 4.2%. Having public or no health insurance, injection
drug use (IDU) or heterosexual risk background (HET), and being nonwh
ite and female were significant predictors of active TB in persons wit
h AIDS. Conclusions: A registries' data match can provide useful infor
mation and result in improved validity for both registries. Although w
omen with AIDS initially appeared to have a higher risk of having acti
ve TB, additional parallel analyses suggested that this effect was pri
marily the result of the 1993 expansion of the definition of AIDS.