This study determines the relation between visual field impairment, vi
sual functioning, and global quality of life in patients with glaucoma
, Binocular visual field impairment was calculated from simultaneous E
sterman visual field testing using the Humphrey automated perimeter. V
isual acuity impairment, defined with the American Medical Association
's Guides to the Evaluation of Permanent Impairment; visual functionin
g, measured with the VF-14 and the field test version of the National
Eye Institute-Visual Functioning Questionnaire; and global quality of
life, assessed with the Medical Outcomes Study 36-Item Short Form Heal
th Survey, were determined in 147 consecutive patients with glaucoma.
None of the Medical Outcomes Study 36-Item Short Form Health Survey do
mains demonstrated more than a weak correlation with visual field impa
irment. The VF-14 scores were moderately correlated (r=-0.58). Of the
National Eye Institute-Visual Functioning Questionnaire scales, periph
eral vision (r=-0.60), distance activities (r=-0.56), and vision-speci
fic dependency (r=-0.56) were moderately correlated with visual field
impairment; vision-specific social functioning, near activities, visio
n-specific role difficulties, general vision, vision-specific mental h
ealth, color vision, and driving were modestly correlated with visual
field impairment (r value between -0.32 and -0.55); visual pain was we
akly correlated with visual field impairment; and general health and v
ision-specific expectations were not notably correlated with visual fi
eld impairment. Statistically adjusting for visual acuity weakened the
correlations, The Medical Outcomes Study 36-Item Short Form Health Su
rvey indicated that our patients with glaucoma were comparable with pr
eviously studied patients without severe systemic medical problems. Ho
wever, the Medical Outcomes Study 36-Item Short Form Health Survey sco
res did not correlate with visual field impairment in our study. Based
on the moderate correlation between binocular visual field impairment
with the VF-14 and the National Eye Institute-Visual Functioning Ques
tionnaire, these questionnaires may be useful among patients with glau
coma.