We have compared the structure of the genomes of rice and hexaploid br
ead wheat, which speciated more than 60 million years ago, by reciproc
al mapping of DNA probes. Results indicate that many wheat chromosomes
contain homoeologous genes and genomic DNA fragments in a similar ord
er to that found on rice chromosomes. This conservation of gene order
along chromosomes differing in DNA content by some 30-fold, may provid
e a basis for novel gene isolation strategies in wheat, one of the wor
ld's major food crop species.