LIFETIME DIAGNOSIS OF PRION TRANSMISSIVE ENCEPHALOPATHIES

Authors
ROIKHEL VM FOKINA GI KONDAKOVA LM SOBOLEV SG POGODINA VV DZHIBLADZE DN GNEZDITSKY VV KASHINA YM PERESEDOV VV SUNGUROV YB KUGOYEV AI CHAIKOVSKAYA RP KONOVALOVA YV SHITIKOVA IY ZAVALISHIN IA
Citation
Vm. Roikhel et al., LIFETIME DIAGNOSIS OF PRION TRANSMISSIVE ENCEPHALOPATHIES, Voprosy virusologii, 42(5), 1997, pp. 203-205
Citations number
20
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
42
Issue
5
Year of publication
1997
Pages
203 - 205
Database
ISI
SICI code
0507-4088(1997)42:5<203:LDOPTE>2.0.ZU;2-6
Abstract
An original method for life-time diagnosis of Greutzfeldt-Jakob's dise ase. a neurodegenerative disease belonging to transmissive spongiform encephalopathies. is proposed. It consists in inoculation of the exami ned biological materials (blood serum and clot) into a continuous cult ure of the rat Gasser's node neurinoma, followed by passages and study of the inoculated culture by morphological methods and electron micro scopy.