Purpose: To evaluate the MR and CT features of pediatric supratentoria
l intra-axial tumors with respect to differential diagnosis and the ro
le of each investigation modality. Material and Methods: MR and CT fin
dings in 40 children with 12 types of pathologically proven histologic
al tumors were reviewed. Results: The location of tumors might be one
clue to differential diagnosis. In our material, cysts (60%), calcific
ations (45%), and intratumoral hemorrhages (27%) were found in the tum
ors. Characteristic features noted in some lesions included: peritumor
al hemosiderin deposition in cavernous angiomas; intratumoral flow voi
d in a choroid plexus carcinoma and in glioblastomas; and hemicerebral
atrophy in germinomas. A comparison between malignant and benign tumo
rs showed perifocal edema and a mass effect to be significantly more c
ommon in malignant lesions. Homogeneous enhancement suggested a benign
tumor and an inhomogeneous pattern represented malignancy, while the
lack of obvious enhancement did not always suggest benignity. Intratum
oral calcium deposition was a not uncommon finding in malignant tumors
. Conclusion: In most cases, the exact diagnosis should be made by his
tological examination but it is important for treatment planning that
the appropriate depiction of tumor extension and tissue characterizati
on be made by MR and CT.