FUNCTIONAL ANALOGS OF HEME PROTEIN ACTIVE-SITES

This article summarizes my research in biomimetic chemistry on the des ign and study of functional models for the active sites of metalloprot eins such as hemoglobin, myoglobin, and cytochrome c oxidase. Particul ar emphasis is placed on the results which have shed light on aspects of biological systems hidden from view by the large protein components of the biological molecules. This account was presented in the form o f a lecture at the ACS National Meeting, San Francisco, April 1997. Th e lecture was given in acceptance of the Alfred Bader Award in Bioinor ganic or Bioorganic Chemistry.