Ms. Ali et al., THE ESTERIFICATION OF GIBBERELLINS WITH DIMETHYLFORMAMIDE DIMETHYL ACETAL (DMFDMA), Zeitschrift fur Naturforschung. B, A journal of chemical sciences, 52(10), 1997, pp. 1237-1244
The key step is to prepare rare gibberellins by converting the more re
adily available gibberellins (GA(3), GA(4), GA(7) and GA(13)) into the
ir methyl eaters. The DMFDMA is employed as an esterifying reagent to
avoid the diazomethane due to its toxic, explosive and hazardous natur
e. It is observed that DMFDMA apart from esterification can also be us
ed as acetylating and epimerizing reagent.