A NOVEL SYNTHESIS OF 9,13-DICIS DOUBLE-BONDS LOCKED RETINOIDS

Authors
QING FL YUE XJ
Citation
Fl. Qing et Xj. Yue, A NOVEL SYNTHESIS OF 9,13-DICIS DOUBLE-BONDS LOCKED RETINOIDS, Tetrahedron letters, 38(46), 1997, pp. 8067-8070
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
46
Year of publication
1997
Pages
8067 - 8070
Database
ISI
SICI code
0040-4039(1997)38:46<8067:ANSO9D>2.0.ZU;2-Q
Abstract
Synthesis of two retinoids in which the 9,13-dicis double bonds were l ocked in cycloalkene or thiophene was described. The key step was carb onylation of vinyl bromide 9 and 16 with carbon monoxide in the presen ce of Pd(PPh3)(4). (C) 1997 Elsevier Science Ltd.