CONFIGURATION OF HEPTOPYRANOSIDE AND HEPTOFURANOSIDE SIDE-CHAINS - 2-ANTHROATE, A POWERFUL CHROMOPHORE FOR EXCITON COUPLED CD

Authors
AKRITOPOULOUZANZE I NAKANISHI K STEPOWSKA H GRZESZCZYK B ZAMOJSKI A BEROVA N
Citation
I. Akritopoulouzanze et al., CONFIGURATION OF HEPTOPYRANOSIDE AND HEPTOFURANOSIDE SIDE-CHAINS - 2-ANTHROATE, A POWERFUL CHROMOPHORE FOR EXCITON COUPLED CD, Chirality, 9(7), 1997, pp. 699-712
Citations number
35
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
Chirality → ACNP
ISSN journal
08990042
Volume
9
Issue
7
Year of publication
1997
Pages
699 - 712
Database
ISI
SICI code
0899-0042(1997)9:7<699:COHAHS>2.0.ZU;2-A
Abstract
The absolute configuration of the acyclic side chain of heptopyranosid es and heptofuranosides was determined by exciton coupled CD, employin g the strongly fluorescent 2-anthroate chromophore. The usage of this chromophore offers significant improvements over previous chemical and spectroscopic procedures since its intense fluorescence greatly facil itates the isolation and HPLC purification at the nanogram scale. The large amplitudes of the bisignate spectra allow CD manipulations in th e 1 x 10(-7) M range. (C) 1997 Wiley-Liss, Inc.