SELENIUM-DIRECTED CONJUGATE ADDITION OF AMINES TO DIMETHYL 2-PHENYLSELENO FUMARATE - REGIO AND DIASTEREOSELECTIVE SYNTHESIS OF 2-PHENYLSELENO-3-AMINO SUCCINATES
M. Bella et al., SELENIUM-DIRECTED CONJUGATE ADDITION OF AMINES TO DIMETHYL 2-PHENYLSELENO FUMARATE - REGIO AND DIASTEREOSELECTIVE SYNTHESIS OF 2-PHENYLSELENO-3-AMINO SUCCINATES, Tetrahedron letters, 38(45), 1997, pp. 7917-7918
Dimethyl 2-phenylseleno fumarate 1 acts as a strong Michael acceptor o
f amines, providing the corresponding 2-phenylseleno-3-amino succinate
s 2a and 2b in very high yields with complete regio-and good diastereo
selectivity. (C) 1997 Elsevier Science Ltd.