SYNTHESIS OF [1]BENZOPYRANO[2,3-B]PYRROL-4(1H)-ONES

Authors
ALBEROLA A ALVARO R ORTEGA AG SANUDO C
Citation
A. Alberola et al., SYNTHESIS OF [1]BENZOPYRANO[2,3-B]PYRROL-4(1H)-ONES, Tetrahedron, 53(47), 1997, pp. 16185-16194
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
47
Year of publication
1997
Pages
16185 - 16194
Database
ISI
SICI code
0040-4020(1997)53:47<16185:SO[>2.0.ZU;2-H
Abstract
2-N-(Acylmethyl)aminochromones were prepared from 2-chlorochromone and alpha-amino ketones (hydrochloride or ketal derivatives) in ethanol/t riethylamine. Their treatment with acetic acid/pyrrolidine led to [1]b enzopyrano[2,3-b]pyrrol-4(1H)-ones, which were subsequently functional ized in C2 by aromatic electrophilic substitution (acetylation, bromin ation or nitration). (C) 1997 Elsevier Science Ltd.