REDUCTIVE LITHIATION OF ARYLALKYL METHYL ETHERS

Authors
AZZENA U CARTA S MELLONI G SECHI A
Citation
U. Azzena et al., REDUCTIVE LITHIATION OF ARYLALKYL METHYL ETHERS, Tetrahedron, 53(47), 1997, pp. 16205-16212
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
47
Year of publication
1997
Pages
16205 - 16212
Database
ISI
SICI code
0040-4020(1997)53:47<16205:RLOAME>2.0.ZU;2-U
Abstract
We have investigated the reductive cleavage of arylalkyl methyl ethers with an excess of lithium metal and a catalytic amount of naphthalene . The reaction proceeds regioselectively in the presence of various su bstituents on the aromatic ring, allowing access to a wide array of ar ylalkyl lithium derivatives, some of which are not easily accessible b y conventional methods. (C) 1997 Elsevier Science Ltd.