DIASTEREOSELECTIVE REDUCTION OF ACYCLIC HYDROXYKETONES AND DIKETONES WITH AN INDIUM HYDRIDE REAGENT

Authors
YAMADA M HORIE T KAWAI M YAMAMURA H ARAKI S
Citation
M. Yamada et al., DIASTEREOSELECTIVE REDUCTION OF ACYCLIC HYDROXYKETONES AND DIKETONES WITH AN INDIUM HYDRIDE REAGENT, Tetrahedron, 53(46), 1997, pp. 15685-15690
Citations number
32
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
46
Year of publication
1997
Pages
15685 - 15690
Database
ISI
SICI code
0040-4020(1997)53:46<15685:DROAHA>2.0.ZU;2-J
Abstract
Hydroxyketones and diketones have been reduced with lithium indium hyd ride to give meso-diols selectively. alpha-Hydroxyketones and alpha-di ketones are reduced to meso-1,2-diols with high diastereoselectivities , whereas the selectivities of beta-hydroxyketones and beta-diketones are less satisfactory. (C) 1997 Elsevier Science Ltd.