SYNTHESIS OF IMIDAZO[1,5-C][1,3]BENZODIAZEPINES VIA AN AZA-WITTIG CARBODIIMIDE-MEDIATED ANNULATION PROCESS/

Authors
MOLINA P TARRAGA A CURIEL D DEARELLANO CR
Citation
P. Molina et al., SYNTHESIS OF IMIDAZO[1,5-C][1,3]BENZODIAZEPINES VIA AN AZA-WITTIG CARBODIIMIDE-MEDIATED ANNULATION PROCESS/, Tetrahedron, 53(46), 1997, pp. 15895-15902
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
46
Year of publication
1997
Pages
15895 - 15902
Database
ISI
SICI code
0040-4020(1997)53:46<15895:SOIVAA>2.0.ZU;2-W
Abstract
The first synthesis of the imidazo[1,5c][1,3]benzodiazepine ring syste m has been carried out by reaction of the iminophosphorane derived fro m the (Z)-5-(o-azidoarylidene)hydantoin with isocyanates. The isomeric (E)-tributyliminophosphorane undergoes intramolecular aza Wittig reac tion to give the imidazo[4,5-b]quinolin-2-one ring. (C) 1997 Elsevier Science Ltd.