8-AMINOQUINOLINES AS ANTICOCCIDIALS .1.

Authors
ARMER RE BARLOW JS DUTTON CJ GREENWAY DHJ GREENWOOD SDW LAD N TOMMASINI I
Citation
Re. Armer et al., 8-AMINOQUINOLINES AS ANTICOCCIDIALS .1., Bioorganic & medicinal chemistry letters, 7(20), 1997, pp. 2585-2588
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
20
Year of publication
1997
Pages
2585 - 2588
Database
ISI
SICI code
0960-894X(1997)7:20<2585:8AA.>2.0.ZU;2-J
Abstract
The proposed ring metabolites of the 8-aminoquinoline antimalarial, pe ntaquine, 1, have been synthesised and their biological activity as an ticoccidial agents investigated in vivo. Several analogues in which th is metabolic pathway had been blocked were also synthesised and their anticoccidial activity measured. (C) 1997 Elsevier Science Ltd.