In several New York City neighborhoods more than 1 in 10 adults and ad
olescents are infected with HIV. Children in these neighborhoods are e
xposed both directly and indirectly to the effects of the HIV epidemic
. Exploratory group interviews were conducted to discover the HIV-rela
ted concerns of adolescent and preadolescent girls and boys living in
a high-seroprevalence neighborhood and to specify the context within w
hich children experienced those concerns. Results indicated that expla
nations about HIV focusing only on transmission and transmission preve
ntion, whether in educational or family settings, may ignore compellin
g concerns of youth. Both risk of HIV and loss of neighbors and relati
ves to HIV permeate daily life but in a way that prevents open discuss
ion. Children are eager to talk about social and personal issues regar
ding HIV.