EVALUATING THE PLASTICITY POTENTIAL OF THE AUDITORY BRAIN-STEM NUCLEUS IN THE RAT

Authors
ILLING RB FORSTER CR HORVATH M
Citation
Rb. Illing et al., EVALUATING THE PLASTICITY POTENTIAL OF THE AUDITORY BRAIN-STEM NUCLEUS IN THE RAT, The American journal of otology, 18(6), 1997, pp. 52-53
Citations number
6
Categorie Soggetti
Otorhinolaryngology
Journal title
The American journal of otology → ACNP
ISSN journal
01929763
Volume
18
Issue
6
Year of publication
1997
Supplement
S
Pages
52 - 53
Database
ISI
SICI code
0192-9763(1997)18:6<52:ETPPOT>2.0.ZU;2-E
Abstract
Objective: To study the adaptation of the auditory brainstem to audito ry loss.Study Design: Growth-associated protein 43 (GAP-43) immunoreac tivity was studied in in rats whose cochleas had been removed. Results and Discussion: Neurons in the lateral superior olive were found to s ynthesize GAP-43 in a pattern that paralleled the changes in GAP-43 im munoreactivity in the cochlear nucleus after cochlear ablation. These findings suggest that new patterns of synaptic communication can be es tablished after damage to the cochlea.