SYNTHESIS OF 2-AROYLMETHYLQUINOLIN-4-ONES VIA THE ADDITION-REACTION OF ORTHO-NITROBENZOYLKETENE TO 1-ARYL-1-TRIMETHYLSILYLOXYETHYLENES

Authors
TODA J SAITOH T SANO T
Citation
J. Toda et al., SYNTHESIS OF 2-AROYLMETHYLQUINOLIN-4-ONES VIA THE ADDITION-REACTION OF ORTHO-NITROBENZOYLKETENE TO 1-ARYL-1-TRIMETHYLSILYLOXYETHYLENES, Heterocycles, 45(10), 1997, pp. 1937-1944
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
45
Issue
10
Year of publication
1997
Pages
1937 - 1944
Database
ISI
SICI code
0385-5414(1997)45:10<1937:SO2VTA>2.0.ZU;2-H
Abstract
Catalytic hydrogenation of 1-aryl-5-(2-nitrophenyl)pentane-1,3,5-trion es A over 10% Pd-C caused selective reduction of the nitro group with concomitant cyclization to give 2-aroylmethylquinolin-4-ones B. This p rovides a simple method of quinolin-4-one synthesis.