DNA CHIP - A BENCH MULTI-REACTOR

Citation
M. Bellis et P. Casellas, DNA CHIP - A BENCH MULTI-REACTOR, MS. Medecine sciences, 13(11), 1997, pp. 1317-1324
Citations number
30
Categorie Soggetti
Medicine, Research & Experimental
Journal title
ISSN journal
07670974
Volume
13
Issue
11
Year of publication
1997
Pages
1317 - 1324
Database
ISI
SICI code
0767-0974(1997)13:11<1317:DC-ABM>2.0.ZU;2-1
Abstract
DNA chip is a revolutionary technology dedicated to large scale study of complex DNA or RNA samples. This review presents the physical princ iples of these devices and the technical solutions developed by the ma in industrial actors of the field. We describe also some applications of the DNA chips: search for mutations in genetic diseases, quantifica tion of gene expression,sequencing by hybridization and development of new therapeutic drugs.