This study examined daily temporal relationships between stress, cogni
tive appraisal, coping, and migraine in a group of young women migrain
eurs sampled from a general population. Participants (N=20) meeting In
ternational Headache Society(1) criteria for migraine with or migraine
without aura provided headache activity, perceived stress, cognitive
appraisal, and coping strategy data across 2 months of data collection
. A time-series analytic approach was used to cross-correlate daily st
ress, appraisal, and coping data with daily headache data controlling
for factors that can inflate correlations in data collected across tim
e. Analyses revealed that between 50% and 70% of subjects showed signi
ficant, substantial, and meaningful temporal correlations between thei
r daily stress and their daily migraine activity. Furthermore, these d
ata support the hypothesis that stress and migraine am reciprocally re
lated lie, cyclically influencing each other across time). In addition
, despite some measurement concerns, our data suggest that cognitive a
ppraisal and coping are also related to migraine activity in a recipro
cal fashion.