HERPES-SIMPLEX VEGETANS - ATYPICAL GENITAL HERPES INFECTION IN A PATIENT WITH COMMON VARIABLE IMMUNODEFICIENCY

Large papillomatous lesions clinically resembling verrucous carcinoma may be caused by viruses other than human papillomavirus. We report a case of recurrent vegetations covering the entire vulva in a pregnant patient with common variable immunodeficiency. Herpes simplex virus wa s recovered from these lesions, The patient did not respond to intrave nous acyclovir, but her lesions dramatically healed with two courses o f intravenous foscarnet. Repeated biopsies may prove necessary in case s such as this to ensure proper diagnoses.