SWERTIFRANCHESIDE, AN HIV REVERSE-TRANSCRIPTASE INHIBITOR AND THE FIRST FLAVONE-XANTHONE DIMER, FROM SWERTIA-FRANCHETIANA

Authors
WANG JN HOU CY LIU YL LIN LZ GIL RR CORDELL GA
Citation
Jn. Wang et al., SWERTIFRANCHESIDE, AN HIV REVERSE-TRANSCRIPTASE INHIBITOR AND THE FIRST FLAVONE-XANTHONE DIMER, FROM SWERTIA-FRANCHETIANA, Journal of natural products, 57(2), 1994, pp. 211-217
Citations number
16
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
57
Issue
2
Year of publication
1994
Pages
211 - 217
Database
ISI
SICI code
0163-3864(1994)57:2<211:SAHRIA>2.0.ZU;2-L
Abstract
The first flavone-xanthone C-glucoside, swertifrancheside, was isolate d from Suertia franchetiana, and its structure was elucidated on the b asis of spectroscopic analysis as -beta-D-glucopyranosyl-4'-oxy-8'-fla vyl)-xanthone. This compound was a moderately potent inhibitor of HIV reverse transcriptase.